Friday, February 21, 2014

Cell therapy shows remarkable ability to eradicate cancer in clinical study

Cell therapy shows remarkable ability to eradicate cancer in clinical study

Date:
February 19, 2014
Source:
Memorial Sloan-Kettering Cancer Center
Summary:
The largest clinical study ever conducted to date of patients with advanced leukemia found that 88% achieved complete remissions after being treated with genetically modified versions of their own immune cells. "These extraordinary results demonstrate that cell therapy is a powerful treatment for patients who have exhausted all conventional therapies," said a senior author. "Our initial findings have held up in a larger cohort of patients, and we are already looking at new clinical studies to advance this novel therapeutic approach in fighting cancer."

 
Cell-based, targeted immunotherapy is a new approach to treating cancer that harnesses the body's own immune system to attack and kill cancerous cells. Unlike with a common virus such as the flu, our immune system does not recognize cancer cells as foreign and is therefore at a disadvantage in eradicating the disease.
Credit: © Voyagerix / Fotolia
 
Cell-based, targeted immunotherapy is a new approach to treating cancer that harnesses the body's own immune system to attack and kill cancerous cells. Unlike with a common virus such as the flu, our immune system does not recognize cancer cells as foreign and is therefore at a disadvantage in eradicating the disease.
Investigators from Memorial Sloan Kettering Cancer Center have reported more encouraging news about one of the most exciting methods of cancer treatment today. The largest clinical study ever conducted to date of patients with advanced leukemia found that 88% achieved complete remissions after being treated with genetically modified versions of their own immune cells. The results were published today in Science Translational Medicine.
"These extraordinary results demonstrate that cell therapy is a powerful treatment for patients who have exhausted all conventional therapies," said Michel Sadelain, MD, PhD, Director of the Center for Cell Engineering at Memorial Sloan Kettering and one of the study's senior authors. "Our initial findings have held up in a larger cohort of patients, and we are already looking at new clinical studies to advance this novel therapeutic approach in fighting cancer."
Adult B cell acute lymphoblastic leukemia (B-ALL), a type of blood cancer that develops in B cells, is difficult to treat because the majority of patients relapse. Patients with relapsed B-ALL have few treatment options; only 30% respond to salvage chemotherapy. Without a successful bone marrow transplant, few have any hope of long-term survival.
In the current study, 16 patients with relapsed B-ALL were given an infusion of their own genetically modified immune cells, called T cells. The cells were "reeducated" to recognize and destroy cancer cells that contain the protein CD19. While the overall complete response rate for all patients was 88%, even those with detectable disease prior to treatment had a complete response rate of 78 percent, far exceeding the complete response rate of salvage chemotherapy alone.
Dennis J. Billy, C.Ss.R, of Wynnewood, Pennsylvania, was one of the first patients to receive this treatment more than two years ago. He was able to successfully undergo a bone marrow transplant and has been cancer-free and back at work teaching theology since 2011. Paolo Cavalli, a restaurant owner from Oxford, Connecticut, remains in complete remission eight months after receiving his personalized T cell treatment.
A History of Scientific Achievements for Cell-Based Therapies
Cell-based, targeted immunotherapy is a new approach to treating cancer that harnesses the body's own immune system to attack and kill cancerous cells. Unlike with a common virus such as the flu, our immune system does not recognize cancer cells as foreign and is therefore at a disadvantage in eradicating the disease. For more than a decade, researchers at Memorial Sloan Kettering have been exploring ways to reengineer the body's own T cells to recognize and attack cancer. In 2003, they were the first to report that T cells engineered to recognize the protein CD19, which is found on B cells, could be used to treat B cell cancers in mice.
"Memorial Sloan Kettering was the first center to report successful outcomes using this CD19-targeted approach in B-ALL patients," said Renier Brentjens, MD, PhD, Director of Cellular Therapeutics at Memorial Sloan Kettering and one of the study's senior authors. "It's extremely gratifying to witness the astonishing results firsthand in my patients, having worked for more than a decade developing this technology from the ground up."   In March 2013, the same team of researchers first reported the results of five patients with advanced B-ALL who were treated with cell therapy. Remarkably, all five patients achieved complete remissions.
Results Demonstrate Potential of New Therapy
In the current study, seven of the 16 patients (44%) were able to successfully undergo bone marrow transplantation -- the standard of care and the only curative option for B-ALL patients -- following treatment. Three patients were ineligible due to failure to achieve a complete remission, three were ineligible due to preexisting medical conditions, two declined, and one is still being evaluated for a potential bone marrow transplant. Historically, only 5% of patients with relapsed B-ALL have been able to transition to bone marrow transplantation.
The study also provides guidelines for managing side effects of cell therapy, which can include severe flu-like symptoms such as fever, muscle pain, low blood pressure, and difficulty breathing, referred to as cytokine release syndrome. The researchers developed diagnostic criteria and a laboratory test that can identify which patients are at greater risk for developing this syndrome.
Additional studies to determine whether cell therapy can be applied to other types of cancer are already underway, and studies to test whether B-ALL patients would benefit from receiving targeted immunotherapy as frontline treatment are being planned.

Story Source: The above story is based on materials provided by Memorial Sloan-Kettering Cancer Center. Note: Materials may be edited for content and length.

Tuesday, February 11, 2014

DJP Healing Formula & Health Miracle Plant - ALOE VERA


DJP Healing Formula and Health Miracle Plant
 ALOE VERA


Feb. 2014  The NORMAL USA revenue driven medical research is very slanted towards profits, therefore is uninterested/blinded from looking to how “Natural herbs/science” can create Healing & Quality Health,. yet, they exist right here on Earth - Nature has already made for us the best source of “anti-aging” and growth with its living Aloe Vera Plant.  We have the fuel - made by Nature - that fuels our macrophages , which produce growth factor, which also orchestrates our growth and health from day one. Macrophages fuel the production of the physical manifestation of genes, of telemeres of stem cells . And now, investigations show we have the only source that fuels our macrophages - the living ALOE plant.

So instead of “turning off the aging genes” we can now fuel the growth cells and systems - the truth of anti-aging is “growth”....HOWEVER - there is limited revenue or profit from ALOE, therefore USA Medical System will Ignore, or even demean, this revenue buster !

A SIMPLE Explanation:

·Aloe Vera Heals - So - taken internally trillions of cells are healed.

·As this healing takes place, Immune Systems have less to do - So YOUR Immune Function gets more efficient repairing fewer & fewer damaged cells/ areas in your body.  Soon there are not many damaged cells or body components remaining, requiring Immune Repairs due to daily intake of Aloe Vera, along with NO chemicals, pollutants, fast or packaged foods, etc. ONLY  eat organic foods!

Following my success in Beating/Curing my 4-2007 diagnosed Stage IV Metasticized Prostate Cancer (NO Chemo or Radiation) ,I invested 14,000+ hours researching strategies that empowers our Immune Systems to beat off diseases and illnesses. My research found that, CATEGORICALLY-  ORGANIC, NON-PROCESSED FOOD IS THE BEST MEDICINE IN THE WORLD !  In addition, the reality of the ALOE Plant as likely the MOST empowering/healing/benefitting Plant on earth.         I have been taking & studying Aloe for 30+ years

Why do we ALL Not know this ?  A reality called marketing-driven product growth created by a POWERFUL widespread desire for wealth/revenue/stock and option prices, etc., that badly distorts most reality. Keep in mind places/entities called Washington, DC, Lobbyists, Super Bowl Ads, Fast Food Chains, Wal-Mart, Made in China, BIG Government, Growth in Entitlements, “Buy Mine, It's the Best”, etc. AND - not all aloe products capture and deliver all that the plant has to offer (or something to the effect that - we don't know about it cause most aloe products (no matter what they claim) are 'dead' and limited to only being anti-inflammatory and are not immune enhancing once they are broken by processing......

Aloe is NOT a good revenue or profit item for food cos. or medical system.!

 Major food cos. make their foods to  Look Good, Smell Good, Taste Good, Be Addictive and LAST a LONG TIME - ALL done with Chemicals that are Un-Natural to our Immune System, therefore immune function must counter the danger & WORK hard!  Marketing is ALSO Brainwashing, Exaggeration, Half Truths, Lies, "Bye Mine - It is the BEST !”

 Keep in Mind: Oriental medicine is operated on the principal -"How can we make the Immune System be  "MORE EFFICIENT" !  USA medicine operated on principal - "How much money can we make per patient so - NO HEAL- NO CURE- NEVER seek causes of health issues" so can create an annuity income stream !

For the sake of brevity here are some valuable supporting tools:

·  Anthony J. Sattilaro, M.D., was president of Methodist Hospital in Philadelphia when he was diagnosed with severe prostate cancer that had spread to his ribs, bones, brain, right shoulder, & testicles. He was operated on & had rib removed, castrated, drugs, pain killers etc. & given the usual AMA poisons.Never seeking the CAUSE !  He became perhaps the most famous advocate for the use of diet against cancer. In his best-selling bookRecalled by Life”, he told how he adopted a low-fat, Macrobiotic diet and far outlived (11 years) the grave prognosis he had been given. The diet he followed is called "Macrobiotic" which is drawn from the best elements of a traditional Asian diet, including generous amounts of rice, whole grains, vegetables, beans, & nuts, . NO –oil, sugar, flour, fish, fruit, and ALL ORGANIC.    Our immune systems are overwhelmed by the chemicals/preservatives (poisons), pesticides, growth hormones, etc. overly used to extend shelf life, make food look/taste & smell good & create revenues from packaged foods.  We are the sickest country due to the money driven monopolistic FDA, Pharmaceutical cos., AMA, it’s MD’s ignoring chemicalized diets as “the cause of most illness & diseases” & MD's staggering abuse of drugs in writing the numerous prescriptions for each patient. This vile & parasitic medical establishment has sickened, maimed, & killed hundreds of millions of people while building a MASSIVE health care industry of ongoing poor health, chemical laden/packaged diets, with a strong overweight public component.
· Highlights - “Confession of a Kamikaze Cowboy” by Dirk Benedict Of the A-Team, Battlestar Galactica, Charlie’s Angels, etc.
·  Dirk’s “Old” Eating habits: Deer, Elk, Beef, Lamb, dairy, eggs, soda, poultry, sugar, chocolate, alcohol, honey, all flour products, coffee, all oils including saturated vegetable oils, salt, junk food, many chemicalized foods resulted in; a diagnosis of Serious Prostate Cancer !
·  Dirk went to Michio Kushi’s (Macrobiotic counselor) 5 room cabin in his Northeastern NH retreat in June 1975, 39 years ago, & beat his cancer with a Plant Based Macrobiotic Diet with:No: TV-Radio-Telephone-Books just Dirk’s typewriter & paper. Adjacent to Loch Lake – 1 mile long ½ mile wide in a builder’s collapsed community (Loch Lake Colony) or ghost town. Quiet place for a 30 year old TV actor with Prostate Cancer

·  A Major Transformation occurred.
·  Here is a BRIEF recap:

·  Breakfast: Oatmeal, Light miso soup with wakame

·  Lunch: Brown rice, lightly sautéed veggies, aduki or black beans cooked long & slowly with various kinds of seaweed added.

·  Dinner: Same as Lunch that was leftovers from Dinner. ALL cooked in heavy iron pots.  Got veggies from surrounding area, concentrated on Dandelion & Roots sautéed in sesame oil, & a ginger compress.

·  Stopped thinking and did meditation – nothing else to do. Hours of walking - alone ! Found food as living things.

·  Found that walking in the rain without his clothes that life was special ! His new Baptism, Re-Birth  Started wearing less & less; no one there; nothing would fit; he’d lost 23 lbs in 6 weeks down to 152

·  We all have cravings (chemically induced & maintained) by a premeditated medical revenue-driven system, run for profits, NOT health.  ENORMOUS research into addicting us so that we “HAVE” to consume packaged chemically laden products (with minimum nutrition) that create revenue for the Medical system.  One heck of a business formula for decades. Dirk strongly condemns the American "No Heal No Cure" medical system !

·  Ignored wild strawberries – just got on hands & knees & smelled them (because he couldn’t have ANY form of sugar) --- Commitment. Went thru a powerful & lonely experience – self exam-renewal-rebirth & the “Old” Dirk Benedict died &  a new one emerged  His new rule #1 - eat to live

·  Dirk got older & felt younger.  Upon return his Mom asked “who was this 18 year old gal knocking on her door” (no haircut for months)   Many asked if he was ok.?  Weight now 132 now a total of 43 lbs. lost

 ·  Difference between Dirk & me, is that I learned about benefits of a High pH, & utilized Verne Varona,  Dr. Zhao,  Dr. Esselstyn & MANY others.  He only had Kushi. I was in NC @ 4,000 feet next to a lake, Dirk was in the mountains of NH , next to a lake, several decades ago.

·  Dirk Benedict’s Confessions of a Kamikaze Cowboy lives today. Dirk Benedict - better known as Faceman from the A-Team & Starbuck in the 1970s version of Battlestar Galactica.  Dirk wrote a book  called Confessions of a Kamikaze Cowboy about how he was diagnosed with cancer but cured himself by adopting a macrobiotic diet.


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I also recommend TURMERIC, LOTS of DEEP Breathing (Oxygen kills bad cells incl. cancer cells) , Garlic, Sun Chlorella, Organic Food, filtered water, Astralagus & NO Sugars, Sodas, Table Salt, Drugs or Red meat, use only certified sea salt.   Seek to ease stress in a stressful society thru Yoga Meditation & related. Respect YOUR MIRACULOUS Immune System !


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Additional Info - by DON PORTER - I am monitoring most activities in DNA, STEM CELL, GENE Research and Related, as interesting strides are being made worldwide.
 

Turning Off the "Aging Genes"
by Staff Writers   Tel Aviv, Israel (SPX) Jan 03, 2014

 Computer algorithm developed by TAU researchers identifies genes that could be transformed to stop the aging process. Restricting calorie consumption is one of the few proven ways to combat aging. Though the underlying mechanism is unknown, calorie restriction has been shown to prolong lifespan in yeast, worms, flies, monkeys, and, in some studies, humans.

Now Keren Yizhak, a doctoral student in Prof. Eytan Ruppin's laboratory at Tel Aviv Univ's. Blavatnik School of Computer Science, and her colleagues have developed a computer algorithm that predicts which genes can be "turned off" to create the same anti-aging effect as calorie restriction. The findings, reported in Nature Communications, could lead to the development of new drugs to treat aging. Researchers from Bar-Ilan University collaborated on the research.  "Most algorithms try to find drug targets that kill cells to treat cancer or bacterial infections," says Yizhak. "Our algorithm is the first in our field to look for drug targets not to kill cells, but to transform them from a diseased state into a healthy one."

A digital laboratory  Prof. Ruppin's lab is a leader in the growing field of genome-scale metabolic modeling or GSMMs. Using mathematical equations and computers, GSMMs describe the metabolism, or life-sustaining, processes of living cells. Once built, the individual models serve as digital laboratories, allowing formerly labor-intensive tests to be conducted with the click of a mouse.  Yizhak's algorithm, which she calls a "metabolic transformation algorithm," or MTA, can take information about any two metabolic states and predict the environmental or genetic changes required to go from one state to the other.

"Gene expression" is the measurement of the expression level of individual genes in a cell, and genes can be "turned off" in various ways to prevent them from being expressed in the cell. In the study, Yizhak applied MTA to the genetics of aging.  After using her custom-designed MTA to confirm previous laboratory findings, she used it to predict genes that can be turned off to make the gene expression of old yeast look like that of young yeast. Yeast is the most widely used genetic model because much of its DNA is preserved in humans.

Some of the genes that the MTA identified were already known to extend the lifespan of yeast when turned off. Of the other genes she found, Yizhak sent seven to be tested at a Bar-Ilan Univ. lab. Researchers there found that turning off two of the genes, GRE3 and ADH2, in actual, non-digital yeast significantly extends the yeast's lifespan. "You would expect about 3% of yeast's genes to be lifespan-extending," said Yizhak. "So achieving a 10-fold increase over this expected frequency, as we did, is very encouraging."

Hope for humans - Since MTA provides a systemic view of cell metabolism, it can also shed light on how the genes it identifies contribute to changes in genetic expression. In the case of GRE3 and ADH2, MTA showed that turning off the genes increased oxidative stress levels in yeast, thus possibly inducing a mild stress similar to that produced by calorie restriction. As a final test, Yizhak applied MTA to human metabolic information. MTA was able to identify a set of genes that can transform 40-70% of the differences between the old and young information from 4 different studies. While currently there is no way to verify the results in humans, many of these genes are known to extend lifespan in yeast, worms, and mice. Next, Yizhak will study whether turning off the genes predicted by MTA prolongs the lifespan of genetically engineered mice.




Her body ravaged by secondary progressive multiple sclerosis, Dr. Terry Wahls spent nearly 4 years dependent upon a tilt-recline wheelchair.  The above photographs reveal the remarkable changes which occurred between 2007 and 2009.  One year after beginning the intensive directed --"Plant Based Organic Diet"  nutrition & neuromuscular electrical stimulation interventions which she designed, Dr. Wahls was able to complete an 18 miles bicycle tour. The following year she completed a trail ride in the Canadian Rockies.  Anyone can replicate her wonderful accomplishments

Dr. Wahls is a clinical Professor of Medicine at the Univ. of Iowa where she sees teaches residents and medical students in primary care and traumatic brain injury clinics. She also conducts clinical research and has over a hundred abstracts, oral presentations and publications in peer-reviewed scientific journals and meetings. Dr. Wahls is in the process of conducting clinical trials testing the efficacy of intensive, directed nutrition and neuromuscular electrical stimulation in the setting of secondary and primary progressive multiple sclerosis.  She is also committed to helping the public learn about the connection between the foods we eat and the health we have, or do not have. Her Food as Medicine lecture series has transformed the lives of thousands. Terry lives in Iowa City with her spouse, Jackie, and has 2 children.

The Above is a TINY example of what is Possible with Organic Foods & Quality Aloe !   My favorite single product with the widest beneficial applications is Herbal Aloe Force, that I Investigated Thoroughly !

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When people learn to eat a plant based diet they can eliminate heart disease & cancer.  It could inaugurate a seismic revolution in our health. Other diseases that can be resolved with a plant based diet include: obesity, asthma, hypertension, stroke, heart attacks, gall stones, diverticulitis, osteoporosis, allergies, rheumatoid arthritis, diabetes, multiple sclerosis, lupus, and a marked decrease in the common western cancers of breast, prostate, colon, endometrial, ovarian, and pancreatic. Dr. Caldwell Esselstyn was a surgeon, clinician & researcher at the Cleveland Clinic. Dr. Esselstyn has been associated with the Cleveland Clinic since 1968. During that time, he has served as President of the Staff & as a member of the Bd. of Governors. He chaired the Clinic’s Breast Cancer Task Force & headed its Section of Thyroid and Parathyroid Surgery. In 1991, Dr. Esselstyn served as Pres. of the American Assoc. of Endocrine Surgeons, That same year he organized the first National Conference on the Elimination of Coronary Artery Disease, which was held in Tucson, AZ. In 1997, he chaired a follow-up conference, the Summit on Cholesterol & Coronary Disease, which brought together more than 500 physicians & health-care workers in Lake Buena Vista, FL. In April, 2005, Dr. Esselstyn became the first recipient of the Benjamin Spock Award for Compassion in Medicine. He received the Distinguished Alumnus Award from the Cleveland Clinic Alumni Assoc. in 2009.

 "If the truth be known coronary artery disease is a toothless Tiger"  

I SUPPORT these quotes 100% !


There is "What we know".  There is "What we don't know".  PROBLEM - There is  "What we don't know, that we don't know". Throw in opinions, beliefs, points-of-view, attitudes, positions, desire to be right, egos, greed, self serving, sophisticated Brainwashing/Marketing & related - then you have quite a formula for frustration. 


Thanks for your dedication to the Truth and Seeking out Natural Healing & Curing methods with Plants, Herbs, Deep Breathing & Organic Food!

                                                                                                         Don Porter

ps:  There is so much mis-information about Aloe - what species (even though Father Zago from Brazil wrote 'Aloe Cures Cancer' - he was using the living aloe arborescens plant in the Brazilian jungle... He concluded that it was/is the aloin's (laxative, bitters) detox stimulation effect that is curing cancer... but he states that you MUST use the Aloe leaves totally unheated, and not cold pressed and not dried... yet companies are now selling bottled Aloe Arborescens and trying to pass it off as not heated (http://aloedecaus.com).... this can be very dangerous as the large healing sugars in the living aloe plant (of all species) are truly the ones that fuel the immune cells - the healing success is using the living plant - not only the detox effect or else - laxatives would cure cancer.... There is only one truly unheated (from field to bottle) whole leaf aloe (aloe barbadensis miller - the species that most companies use as it is highest in the Beta-Glucomannas unique to aloe and documented scientific research) that is 100% purified (from all microorganisms and all its laxative) that delivers ALL the living healing plant has to offer (with no harshness so it can be taken daily, by all ages and types, and in high therapeutic dosages if needed).  The misinformation about health in general is appalling and when it comes to the truth about the aloe plant it is down right absurd. The truth is in the pudding... there is only one raw aloe purification process and their Liquified Aloe Barbadensis MIller has been the top selling Aloe product in health food stores nationally according to SPINS statistics since 2011 - and this was accomplished by 'word of mouth'... its effectiveness has grown this product to #1 - not its 'marketing' !! 

Please see - www.herbalanswers.com    It is my position that seeking to identify the actual facts that are required when identifying reality/truth about aloe,  is Crucial to your Overall Good Health.


Disclaimer: I am not a doctor; thus, I have not been formally “miseducated.” I am not certified in medicine; therefore, there is no certificate or diploma disgracing the interior of my home or office and no monument to the biggest revenue generating fraud ever perpetrated on human kind. This Blog/website/Protocol  is for educational purposes only. It is not intended as a substitute for the diagnosis, treatment, or advice of a qualified, licensed medical professional. The facts presented are offered as information only, my experiences in beating Stage IV caner, not medical advice, and in no way should anyone infer that I am practicing medicine. A conscious effort has been made to present information on my experiences that are both accurate and truthful. Much is based on Dr. Otto Warburg.My statements regarding alternative treatments for cancer have not been evaluated by the FDA.